 Bartola Esqueda | Partner or wife | | | | |
| Ignacia Lopez Esqueda | Daughter | | | | |
 Pelagio Serna Lopez | Grandson | Calvillo, Calvillo, Aguascalientes, Mexico | 27 Mar 1825 | | |
| Florentina Serna Medina | Great granddaughter | Jaltiche, Aguascalientes, Mexico | 17 Mar 1850 | | |
| Basilio Serna Medina | Great grandson | | 1860 | | |
| Ramon Serna Medina | Great grandson | La Villita, Jalpa, Zacatecas, Mexico | 1870 | | |
| Alfonso Serna Gonzalez | Second grandson | | | | |
| Bartolo Casillas Serna | Second grandson | | | | |
| Maria Merced Casillas Serna | Second granddaughter | La Villita, Jalpa, Zacatecas, Mexico | 1872 | | |
| Celso Casillas Serna | Second grandson | La Villita, Jalpa, Zacatecas, Mexico | 1878 | | |
| Magdaleno Casillas Serna | Second grandson | La Villita, Jalpa, Zacatecas, Mexico | 22 Jul 1885 | | |
| Manuel Serna Covarrubias | Second grandson | La Villita, Jalpa, Zacatecas, Mexico | 26 Jan 1895 | | |
| Fidencio Serna Gonzalez | Second grandson | Guatimala, Huanusco, Zacatecas, Mexico | 14 Nov 1917 | | |
| Ludi Serna Loera | Third granddaughter | | | | |
| Esequiel Medina Casillas | Third grandson | La Villita, Jalpa, Zacatecas, Mexico | 1889 | | |
| Magdaleno Medina Casillas | Third grandson | Villita de Arriba, Jalpa, Zacatecas, Mexico | 18 Jul 1894 | | |
| Maria Guadalupe Medina Casillas | Third granddaughter | La Villita, Jalpa, Zacatecas, Mexico | 10 Dec 1896 | | |
| Esther Medina Casillas | Third granddaughter | La Villita, Jalpa, Zacatecas, Mexico | 1903 | | |
| Manuel Casillas Mora | Third grandson | La Villita, Jalpa, Zacatecas, Mexico | 16 Jul 1909 | | |
| Bartolo Casillas Flores | Third grandson | La Villita, Jalpa, Zacatecas, Mexico | 04 Oct 1915 | | |
| Alberto Medina Lara | Second grandson-in-law | La Villita, Jalpa, Zacatecas, Mexico | 1866 | | |
| Maria Guadalupe Casillas Valdovinos | Third granddaughter-in-law | La Villita, Jalpa, Zacatecas, Mexico | 1894 | | |
| Jose Maria Guerrero | Third grandson-in-law | | 1896 | | |
