 Maria Ruiz de Esparza (de Ulloa, Ulloa y Ruiz de Esparza) | Partner or wife | | | | |
 Jose de Ulloa | Son | | | | |
| Josefa de Ulloa y Ruiz de Esparza (Villagrana) | Daughter | | 1630 | | |
| Francisco de Ulloa | Son | | 1631 | | |
| Bernarda de Ulloa Flores | Granddaughter | | | | |
| Leonor de Ulloa Flores | Grandson | | | | |
| Maria Ruiz de Esparza (Carlos de Godoy) | Granddaughter | | | | |
| Gertrudis Villagrana Ulloa (Gonzalez Ruiz de Esparza) | Granddaughter | Teocaltiche, Teocaltiche, Jalisco, Mexico | 1667 | | |
| Juana Flores (Ruiz de Esparza) | Daughter-in-law | | | | |
| Juan Villagran | Son-in-law | | ~1630 | | |
| Joseph Carlos de Godoy (de Ulloa) | Grandson-in-law | | | | |
| Domingo de Llamas Rodriguez | Grandson-in-law | Tlaltenango de Sanchez Roman, Tlaltenango de Sanchez Roman, Zacatecas, Mexico | 02 Nov 1631 | | |
| Agustin Carlos de Godoy | Grandson-in-law | | 1639 | | |
| Nicolas Gonzalez Ruiz de Esparza | Grandson-in-law | Aguascalientes, Aguascalientes, Aguascalientes, Mexico | ~1661 | | |
